database / nootropic
Cortagen
also known as AEDP peptide
Research reference only. The observations below are recorded in the cited literature. Nothing here is advice or a recommendation, and no dosing information is published on this site.
Sequence
AEDP
Ala-Glu-Asp-Pro
- hydrophobic
- positive
- negative
- polar
- aromatic
- glycine
- proline
- cysteine
No independent molecular weight was available to check the sequence against.
Molecular data
| molecular formula | not characterised |
|---|---|
| molecular weight | 430.41 Da (computed from sequence) |
| computed backbone mass | 430.41 Da |
| length | 4 residues |
| net charge (pH 7.4) | -2 |
| mean hydropathy | -1.7 |
| half-life | not characterised |
| delivery route | not characterised |
| PubChem CID | not characterised |
| PDB | not characterised |
| UniProt parent | not characterised |
Mechanism
Khavinson-series tetrapeptide studied in peripheral nerve models.
Reported targets: not established
Experimental structure
No experimental structure of this peptide is deposited in the PDB. Nothing is rendered here — a predicted fold would not be a structure, and this site does not draw one.
Reported effects
Each row is an outcome described in the literature indexed for this peptide. Reported in the cited work — not a claim, not a recommendation.
| reported outcome | where it appears |
|---|---|
| nerve regeneration in models | EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON THE … Georgian medical news 2023 |
Literature (5)
EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON THE "OLD" CHROMATIN — Georgian medical news 2023
abstract not reproduced — this record is not open-access, so it is linked rather than copied.
publisher record ↗ · PMID 37042594
Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray — Neuro endocrinology letters 2004
abstract not reproduced — this record is not open-access, so it is linked rather than copied.
publisher record ↗ · PMID 15159690
[Cortexin and cortagen as correcting agents in functional and metabolic disorders in the brain in chronic ischemia] — Eksperimental'naia i klinicheskaia farmakologiia 2011
abstract not reproduced — this record is not open-access, so it is linked rather than copied.
publisher record ↗ · PMID 21476278
Effect of tetrapeptide cortagen on regeneration of sciatic nerve — Bulletin of experimental biology and medicine 2000
abstract not reproduced — this record is not open-access, so it is linked rather than copied.
publisher record ↗ · PMID 11276314 · DOI 10.1023/a:1017532001908
Tissue-specific effects of peptides — Bulletin of experimental biology and medicine 2001
abstract not reproduced — this record is not open-access, so it is linked rather than copied.
publisher record ↗ · PMID 11713572 · DOI 10.1023/a:1013058701974