the alphabet
Twenty letters
Every sequence in this index is written in the same twenty-letter alphabet. Colour is side-chain chemistry throughout the site — this is the key, and the bars show how often each residue actually appears across all 62 indexed sequences.
AAla
Alanine
hydrophobic
- hydropathy
- +1.8
- charge
- 0
- residue mass
- 71.1 Da
RArg
Arginine
positive
- hydropathy
- -4.5
- charge
- +1
- residue mass
- 156.2 Da
NAsn
Asparagine
polar
- hydropathy
- -3.5
- charge
- 0
- residue mass
- 114.1 Da
DAsp
Aspartic acid
negative
- hydropathy
- -3.5
- charge
- −1
- residue mass
- 115.1 Da
CCys
Cysteine
cysteine
- hydropathy
- +2.5
- charge
- 0
- residue mass
- 103.1 Da
EGlu
Glutamic acid
negative
- hydropathy
- -3.5
- charge
- −1
- residue mass
- 129.1 Da
QGln
Glutamine
polar
- hydropathy
- -3.5
- charge
- 0
- residue mass
- 128.1 Da
GGly
Glycine
glycine
- hydropathy
- -0.4
- charge
- 0
- residue mass
- 57.1 Da
HHis
Histidine
positive
- hydropathy
- -3.2
- charge
- 0
- residue mass
- 137.1 Da
IIle
Isoleucine
hydrophobic
- hydropathy
- +4.5
- charge
- 0
- residue mass
- 113.2 Da
LLeu
Leucine
hydrophobic
- hydropathy
- +3.8
- charge
- 0
- residue mass
- 113.2 Da
KLys
Lysine
positive
- hydropathy
- -3.9
- charge
- +1
- residue mass
- 128.2 Da
MMet
Methionine
hydrophobic
- hydropathy
- +1.9
- charge
- 0
- residue mass
- 131.2 Da
FPhe
Phenylalanine
aromatic
- hydropathy
- +2.8
- charge
- 0
- residue mass
- 147.2 Da
PPro
Proline
proline
- hydropathy
- -1.6
- charge
- 0
- residue mass
- 97.1 Da
SSer
Serine
polar
- hydropathy
- -0.8
- charge
- 0
- residue mass
- 87.1 Da
TThr
Threonine
polar
- hydropathy
- -0.7
- charge
- 0
- residue mass
- 101.1 Da
WTrp
Tryptophan
aromatic
- hydropathy
- -0.9
- charge
- 0
- residue mass
- 186.2 Da
YTyr
Tyrosine
aromatic
- hydropathy
- -1.3
- charge
- 0
- residue mass
- 163.2 Da
VVal
Valine
hydrophobic
- hydropathy
- +4.2
- charge
- 0
- residue mass
- 99.1 Da
Hydropathy values are the Kyte-Doolittle scale. Charge is the formal side-chain charge at pH 7.4. Residue mass is the average mass contributed to a chain (free amino acid minus water). Colour scheme is Clustal-style, by side-chain chemistry.